Regulação de vaga do acidente vascular cerebral hiperagudo: perfil epidemiológico / Vacancy coordination for hyperacute stroke: epidemiological profile / Regulación de vacantes para accidente cerebrovascular hiperagudo: perfil epidemiológico

Objetivo: identificar o perfil epidemiológico e clínico dos casos regulados como acidente vascular cerebral hiperagudo em um hospital referenciado. Método: trata-se de um estudo quantitativo, retrospectivo, que analisou 131 fichas de casos regulados com hipótese diagnóstica de acidente vascular cerebral hiperagudo, em um hospital referenciado. Submeteram-se os dados coletados à análise estatística descritiva com o programa SAS 9.4, considerando-se p<0,05 como o nível de significância. Resultados: detectou-se que a idade média dos pacientes foi de 67,44 anos, do sexo masculino, com sintoma mais frequente a fraqueza de membros, em 119 casos e 107 na referência. Verificou-se a ocorrência do acidente vascular isquêmico em 79 casos e a etiologia de síndrome lacunar em 33. Registra-se que 100 pacientes obtiveram alta hospitalar e 20 faleceram. Percebeuse a significância estatística (p≤0,05) entre os resultados clínicos com o valor do teste de glicemia capilar e a presença do desvio de rima labial no serviço de origem. Conclusão: observa-se que os achados estatisticamente significativos revelam a necessidade da criação de protocolos específicos e a educação permanente das equipes.(AU)

Objective: to identify the epidemiological and clinical profile of cases coordinated as hyperacute stroke in a reference hospital. Method: this is a quantitative retrospective study in which we analyzed 131 medical records of hyperacute stroke cases coordinated in a reference hospital. The data collected were submitted to descriptive statistical analysis with the SAS 9.4 program, considering a p <0.05 statistically significant. Results: the mean age of patients was 67.44 years, most were male, and limb weakness was the most frequent symptom, in 119 cases and 107 referral cases. The occurrence of ischemic stroke was found in 79 cases, and the etiology of lacunar syndrome in 33. One hundred patients were discharged from the hospital and 20 died. A statistically significant (p≤0.05) relation was found between clinical results concerning the capillary glycemia values and the presence of lip rhyme deviation in the service of origin. Conclusion: the statistically significant findings reveal the need to create specific protocols and to implement permanent education of the teams.(AU)

Objetivo: identificar el perfil epidemiológico y clínico de los casos coordinados como ictus hiperagudo en un hospital de referencia. Método: se trata de un estudio cuantitativo retrospectivo en el que analizamos 131 historias clínicas de casos de ictus hiperagudo regulados en un hospital de referencia. Los datos recolectados fueron sometidos a análisis estadístico descriptivo con el programa SAS 9.4, considerando p <0.05 estadísticamente significativa. Resultados: la edad media de los pacientes fue de 67,44 años, la mayoría eran varones y la debilidad de las extremidades fue el síntoma más frecuente, en 119 casos y 107 casos referenciados. La ocurrencia de ictus isquémico se encontró en 79 casos originales y la etiología del síndrome lacunar en 33. Cien pacientes fueron dados de alta del hospital y 20 fallecieron. Se encontró relación estadísticamente significativa (p≤0.05) entre los resultados clínicos de los valores de glucemia capilar y la presencia de desviación de la rima labial en el servicio de origen. Conclusión: los hallazgos estadísticamente significativos revelan la necesidad de crear protocolos específicos e implementar la educación permanente de los equipos.(AU)

Cellulose biomembrane versus collagenase dressing for the treatment of chronic venous ulcers: a randomized, controlled clinical trial.

Cellulose biomembranes may be used for difficult-to-treat ulcers. To assess the efficacy and safety of cellulose biomembranes compared to a collagenase dressing for the treatment of chronic venous ulcers. A randomized, controlled clinical trial was performed using two groups: one treated with collagenase dressing and the other with cellulose biomembrane over a 90-day (T90) period. Both groups received compression therapy. The primary outcome was reduction in ulcer area at T90. Secondary outcomes were healing status, decrease in devitalized tissue and exudate, vascular fraction, change in quality of life, and safety. We randomized 46 participants with 73 venous ulcers (21 with 36 ulcers in the collagenase group and 25 with 37 ulcers in the biomembrane group). A decrease in ulcer area occurred at T90 in both groups, but the difference was not significant. Complete healing before T90 occurred for seven ulcers in the collagenase group and 12 ulcers in the biomembrane group, without significant difference. However, the biomembrane promoted increased precocious healing (p = 0.02). Improved bed vitality and quality of life was observed as a function of time (p < 0.01), but this was not significant between the groups. Immunohistochemical analysis of CD34 showed an increase in vascular fraction in both groups (p < 0.01), with a higher level in the biomembrane group (p < 0.05). No adverse events were considered related to the products. Cellulose biomembranes, in combination with compressive therapy, are effective and safe for the treatment of venous ulcers and provide results similar to those with collagenase treatment.